Biopsy and Ablation of H3K27 Glioma Using Skull-Mounted Smartframe Device

Technical Case Report

Jiri Bartek, Ali Alattar, Margret Jensdottir, Clark C Chen

Research output: Contribution to journalArticle

Abstract

Background: Clearpoint Smartframe is a magnetic resonance imaging−compatible stereotactic system often used to perform magnetic resonance imaging−guided biopsies. The system is typically mounted on the scalp through screws that pierce the skin and penetrate the outer table of the cranium. However, the frame can also be configured to be mounted directly onto the skull. Case Description: Here, we describe the clinical context well suited for a skull-mount Clearpoint Smartframe surgery. The patient suffered from a subcentimeter right parafourth ventricular contrast-enhancing lesion with hydrocephalus and underwent a right suboccipital needle biopsy followed by an occipital ventriculoperitoneal shunt. Although the hydrocephalus resolved with the ventriculoperitoneal shunt, the biopsy sample proved nondiagnostic. The patient underwent a second procedure during which the Clearpoint Smartframe was mounted onto the skull through space dissected free during the previous surgery. Diagnostic biopsy (H3K27 glioma)was performed followed by stereotactic laser ablation of the lesion. Conclusions: We describe a case in which the skull mount Clearpoint Smartframe was used to biopsy and ablate a midline H3K27 glioma.

Original languageEnglish (US)
Pages (from-to)436-441
Number of pages6
JournalWorld neurosurgery
Volume127
DOIs
StatePublished - Jul 1 2019

Fingerprint

Skull
Glioma
Biopsy
Equipment and Supplies
Ventriculoperitoneal Shunt
Hydrocephalus
Magnetic Resonance Spectroscopy
Laser Therapy
Needle Biopsy
Scalp
Skin

Keywords

  • Clearpoint Smartframe
  • Glioblastoma
  • Laser interstitial thermal therapy
  • Neurosurgery
  • Skull mount
  • Stereotactic biopsy
  • Stereotactic laser ablation

PubMed: MeSH publication types

  • Journal Article

Cite this

Biopsy and Ablation of H3K27 Glioma Using Skull-Mounted Smartframe Device : Technical Case Report. / Bartek, Jiri; Alattar, Ali; Jensdottir, Margret; Chen, Clark C.

In: World neurosurgery, Vol. 127, 01.07.2019, p. 436-441.

Research output: Contribution to journalArticle

Bartek, Jiri ; Alattar, Ali ; Jensdottir, Margret ; Chen, Clark C. / Biopsy and Ablation of H3K27 Glioma Using Skull-Mounted Smartframe Device : Technical Case Report. In: World neurosurgery. 2019 ; Vol. 127. pp. 436-441.
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