Biopharmaceutical considerations of opioid analgesics in models of self-administration: Review and summary

Carolyn A. Fairbanks; Cristina D. Peterson

doi:10.1007/978-1-4939-1856-0_6

Biopharmaceutical considerations of opioid analgesics in models of self-administration: Review and summary

Carolyn A. Fairbanks, Cristina D. Peterson

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Abstract

Throughout this volume we have discussed the opioid analgesics and the propensity for subjects with established chronic pain to develop opioid-induced addiction. The class of opioid analgesic compounds and pharmaceutical dosage forms include not only chemicals with similar characteristics but also some significant distinctions that can impact the ultimate pharmacological effects on both analgesia and potential for addiction. In developing and/or implementing animal models of opioid addiction in the state of chronic pain it is valuable to be cognizant of the physicochemical and pharmacological characteristics of specific opioid analgesics. The objective of this chapter is to feature biopharmaceutical aspects of a series of the most common prescription analgesics opioids.

Original language	English (US)
Title of host publication	Neurobiological Studies of Addiction in Chronic Pain States
Publisher	Springer New York
Pages	81-107
Number of pages	27
ISBN (Electronic)	9781493918560
ISBN (Print)	9781493918553
DOIs	https://doi.org/10.1007/978-1-4939-1856-0_6
State	Published - Jan 1 2014

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© Springer Science+Business Media New York 2014.

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Biopharmaceutical considerations of opioid analgesics in models of self-administration: Review and summary

Abstract

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