Abstract
In this paper, we present a ultra high sensitive (Zeptomole, 10 -21) technique to enable the detection of any potential low abundance biomarkers. We demonstrated for the first time the detection of sub 13nm high-moment magnetic nanoparticle and the implementation of a novel magnetoresistive (GMR) biosensor concept with higher sensitivity and 10 times lower external field in real biomarker sensing schemes. A potential lung cancer biomarker, interleukin-6 (IL-6), was successfully detected with extremely low concentration (as few as only 200 pieces of IL-6). Together with other features of GMR sensor systems like low-cost, portability, easy-to-use, our demonstrated device may lead to future family-based personalized medicine for cancer prevention.
Original language | English (US) |
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Pages (from-to) | 5432-5435 |
Number of pages | 4 |
Journal | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference |
DOIs | |
State | Published - 2009 |
Event | 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009 - Minneapolis, MN, United States Duration: Sep 2 2009 → Sep 6 2009 |
PubMed: MeSH publication types
- Journal Article
- Research Support, Non-U.S. Gov't
- Research Support, U.S. Gov't, Non-P.H.S.