Biology evolves to fight chemistry

Research output: Contribution to journalShort surveypeer-review

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A human enzyme variant, PON1-G3C9, accidentally catalyzes the hydrolysis of organophosphorus chemical weapons. In this issue of Chemistry & Biology, Goldsmith and coworkers describe a new PON1 variant with improved hydrolysis by several hundred fold; enough that it may protect animals from a toxic dose.

Original languageEnglish (US)
Pages (from-to)435-437
Number of pages3
JournalChemistry and Biology
Issue number4
StatePublished - Apr 20 2012


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