Biological chemistry of organotin compounds: Interactions and dealkylation by dithiols

Bethany A. Buck-Koehntop, Fernando Porcelli, John L. Lewin, Christopher J. Cramer, Gianluigi Veglia

Research output: Contribution to journalReview articlepeer-review

42 Scopus citations

Abstract

In this paper, we review our past and current efforts toward the elucidation of the biological chemistry of organotin compounds. In particular, we cover two prominent aspects of organotin compounds: their reactivity toward biological dithiols, and their degradation (or metabolization) mechanism using a combination of experimental and computational techniques.

Original languageEnglish (US)
Pages (from-to)1748-1755
Number of pages8
JournalJournal of Organometallic Chemistry
Volume691
Issue number8
DOIs
StatePublished - Apr 1 2006

Keywords

  • CD spectroscopy
  • ESI-MS
  • Fluorescence spectroscopy
  • NMR
  • Organotin(IV) compounds
  • Stannin

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