Biodegradation of carbamazepine using freshwater microalgae Chlamydomonas mexicana and Scenedesmus obliquus and the determination of its metabolic fate

Jiu Qiang Xiong, Mayur B. Kurade, Reda A I Abou-Shanab, Min Kyu Ji, Jaeyoung Choi, Jong Oh Kim, Byong Hun Jeon

Research output: Contribution to journalArticlepeer-review

137 Scopus citations

Abstract

This study evaluated the toxicity and cellular stresses of carbamazepine (CBZ) on Chlamydomonas mexicana and Scenedesmus obliquus, and its biodegradation by both microalgal species. The growth of both microalgal species decreased with increase of CBZ concentration. The growth of S. obliquus was significantly inhibited (97%) at 200 mg CBZ L-1, as compared to the control after 10days; whereas, C. mexicana showed 30% inhibition at the same experimental conditions. Biochemical characteristics including total chlorophyll, carotenoid contents and enzyme activities (SOD and CAT) for both species were affected by CBZ at relatively high concentration. C. mexicana and S. obliquus could achieve a maximum of 35% and 28% biodegradation of CBZ, respectively. Two metabolites (10,11-dihydro-10,11-expoxycarbamazepine and n-hydroxy-CBZ) were identified by UPLC-MS, as a result of CBZ biodegradation by C. mexicana. This study demonstrated that C. mexicana was more tolerant to CBZ and could be used for treatment of CBZ contaminated wastewater.

Original languageEnglish (US)
Pages (from-to)183-190
Number of pages8
JournalBioresource Technology
Volume205
DOIs
StatePublished - Apr 1 2016

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the South Korea government (MSIP) (No. NRF-2013R1A2A2A07069183 ).

Publisher Copyright:
© 2016 Elsevier Ltd.

Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.

Keywords

  • Biodegradation
  • Bioremediation
  • C. mexicana
  • Carbamazepine
  • Emerging contaminants

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