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Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: Facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors

  • Amit S. Kalgutkar
  • , Brenda C. Crews
  • , Scott W. Rowlinson
  • , Alan B. Marnett
  • , Kevin R. Kozak
  • , Rory P. Remmel
  • , Lawrence J. Marnett

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Pharmacology, Toxicology and Pharmaceutical Science