Biochemical effects of the plant Lantana camara on guinea pig liver mitochondria

O. P. Sharma, H. P.S. Makkar, R. K. Dawra

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Lantana camara caused, in guinea pigs, a decrease in hepatic mitochondrial protein content. The phospholipid to protein ratio did not change but there was a marked increase in the cholesterol to protein ratio and the cholesterol to phospholipid ratio. Enzyme activities of succinic dehydrogenase, glutamate dehydrogenase, cytochrome oxidase and Mg2+-ATPase increased, while the activity of NADH-ferricyanide reductase remained unaffected. Mitochondrial swelling, in the absence or presence of ascorbic acid, decreased in hepatic mitochondria from lantana-intoxicated guinea pigs.

Original languageEnglish (US)
Pages (from-to)783-786
Number of pages4
JournalToxicon
Volume20
Issue number4
DOIs
StatePublished - 1982

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