Bilateral subthalamic nucleus stimulation for the treatment of Parkinson's disease: results of six patients.

Sharon K. Eriksen, Paul J. Tuite, Robert E. Maxwell, Mary Sullivan, Walter C. Low, Timothy J. Ebner

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

In this study, researchers evaluated the effect of bilateral subthalamic nucleus stimulation on various measures of Parkinson's disease. Assessments were completed before and after surgery in a double-blind fashion under the following six conditions: (a) on medication, (b) off medication, (c) on medication/on stimulation, (d) on medication/off stimulation, (e) off medication/on stimulation, and (f) off medication/off stimulation. On average, improvement was noted in all areas including the Unified Parkinson's Disease Rating Scale, Schwab and England Activities of Daily Living Scale, Modified Hoehn and Yahr Staging, and timed tests: In addition, dyskinesia duration and dyskinesia disability were reduced.

Original languageEnglish (US)
Pages (from-to)223-231
Number of pages9
JournalThe Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses
Volume35
Issue number4
DOIs
StatePublished - Aug 2003

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