Bilateral Ovarian B-Lineage Lymphoblastic Lymphoma with MLL Gene Rearrangement: A Novel Case in Infancy

Alyssa M. Larish, Michelle Dolan, Tim Casey, Joanna L. Perkins

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Mixed-lineage leukemia (MLL) gene rearrangements have rarely been reported in pediatric lymphoma despite their high prevalence in pediatric leukemia. We present a case of an infant with bilateral ovarian B-lineage lymphoblastic lymphoma with MLL gene rearrangement. We also briefly summarize the clinicopathologic significance of MLL gene rearrangements, and review the reported cases of pediatric ovarian lymphoma with and without MLL rearrangement.

Original languageEnglish (US)
Pages (from-to)e215-e217
JournalJournal of pediatric hematology/oncology
Volume37
Issue number4
DOIs
StatePublished - Dec 1 2015

Keywords

  • MLL gene rearrangement
  • childhood cancer
  • lymphoblastic lymphoma
  • ovarian lymphoma

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