Abstract
The blue tongue virus core (BTVC) particle is the biggest molecular structure determined to date by X-ray crystallography. The atomic model shows that the inner core particle of 120 VP3 subunits guides the assembly of an outer shell with 780 VP7 subunits. The structure may lead to new targets for particle based anti-viral agents and to experiments to refine the details of the proposed virus assembly pathway.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 849-854 |
| Number of pages | 6 |
| Journal | Nature Structural Biology |
| Volume | 5 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 1998 |
| Externally published | Yes |