Bieyclic bases . Synthesis and stereochemical studies of chiral 5‐substituted N‐tosyl‐2‐azabicyclo[2.2.1[ heptanes

Philip S Portoghese; D. L. Lattin; V. G. Telang

doi:10.1002/jhet.5570080618

Bieyclic bases . Synthesis and stereochemical studies of chiral 5‐substituted N‐tosyl‐2‐azabicyclo[2.2.1[ heptanes

Philip S Portoghese, D. L. Lattin, V. G. Telang

Medicinal Chemistry

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Abstract

The synthesis of chiral exo and endo 5‐sulbstituted N‐losyl‐2‐azabicyclo[2.2.1]heptanes is reported. The nearly identical exo‐endo equilibrium ratios of the title compounds and the carbocyclic analogs suggest that their geometries and sterie interactions are quite similar.

Original language	English (US)
Pages (from-to)	993-998
Number of pages	6
Journal	Journal of Heterocyclic Chemistry
Volume	8
Issue number	6
DOIs	https://doi.org/10.1002/jhet.5570080618
State	Published - Dec 1971

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10.1002/jhet.5570080618

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title = "Bieyclic bases . Synthesis and stereochemical studies of chiral 5‐substituted N‐tosyl‐2‐azabicyclo[2.2.1[ heptanes",

abstract = "The synthesis of chiral exo and endo 5‐sulbstituted N‐losyl‐2‐azabicyclo[2.2.1]heptanes is reported. The nearly identical exo‐endo equilibrium ratios of the title compounds and the carbocyclic analogs suggest that their geometries and sterie interactions are quite similar.",

author = "Portoghese, {Philip S} and Lattin, {D. L.} and Telang, {V. G.}",

year = "1971",

month = dec,

doi = "10.1002/jhet.5570080618",

language = "English (US)",

volume = "8",

pages = "993--998",

journal = "Journal of Heterocyclic Chemistry",

issn = "0022-152X",

publisher = "John Wiley and Sons Inc.",

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TY - JOUR

T1 - Bieyclic bases . Synthesis and stereochemical studies of chiral 5‐substituted N‐tosyl‐2‐azabicyclo[2.2.1[ heptanes

AU - Portoghese, Philip S

AU - Lattin, D. L.

AU - Telang, V. G.

PY - 1971/12

Y1 - 1971/12

N2 - The synthesis of chiral exo and endo 5‐sulbstituted N‐losyl‐2‐azabicyclo[2.2.1]heptanes is reported. The nearly identical exo‐endo equilibrium ratios of the title compounds and the carbocyclic analogs suggest that their geometries and sterie interactions are quite similar.

AB - The synthesis of chiral exo and endo 5‐sulbstituted N‐losyl‐2‐azabicyclo[2.2.1]heptanes is reported. The nearly identical exo‐endo equilibrium ratios of the title compounds and the carbocyclic analogs suggest that their geometries and sterie interactions are quite similar.

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DO - 10.1002/jhet.5570080618

M3 - Article

AN - SCOPUS:84980233138

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VL - 8

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EP - 998

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JF - Journal of Heterocyclic Chemistry

IS - 6

ER -

Bieyclic bases . Synthesis and stereochemical studies of chiral 5‐substituted N‐tosyl‐2‐azabicyclo[2.2.1[ heptanes

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