Basic Science: Social, Vocational, and Psychological Influences on Pain Perception

Elena Averbakh, Matthew Chung, Ratan K. Banik, Thomas Chai

Research output: Chapter in Book/Report/Conference proceedingChapter


Many factors influence an individual’s experience of pain. The pain experience has been best understood based on the biopsychosocial model that includes overall summation of physical, emotional, and perceptual inputs. When a pain signal is initiated due to injury, peripheral pathways are activated and a signaling cascade occurs via the dorsal horn to higher centers of the central nervous system. This pathway, and the signals along its way, have many variables and influences. For instance, mental health disorders such as major depression and generalized anxiety disorder have significant influence on this pathway. Other factors such as age, gender, education, social, and vocational factors play a significant role in an individual’s experience of pain.

Original languageEnglish (US)
Title of host publicationAnesthesiology In-Training Exam Review
Subtitle of host publicationRegional Anesthesia and Chronic Pain
PublisherSpringer International Publishing
Number of pages5
ISBN (Electronic)9783030872663
ISBN (Print)9783030872656
StatePublished - Jan 1 2022

Bibliographical note

Publisher Copyright:
© The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.


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