Bacterial protein acetylation: The dawning of a new age

Hu Linda I., Lima Bruno P., Wolfe Alan J.

Research output: Contribution to journalReview articlepeer-review

134 Scopus citations


Protein acetylation has historically been considered a predominantly eukaryotic phenomenon. Recent evidence, however, supports the hypothesis that acetylation broadly impacts bacterial physiology. To explore more rapidly the impact of protein acetylation in bacteria, microbiologists can benefit from the strong foundation established by investigators of protein acetylation in eukaryotes. To help advance this learning process, we will summarize the current understanding of protein acetylation in eukaryotes, discuss the emerging link between acetylation and metabolism and highlight the best-studied examples of protein acetylation in bacteria.

Original languageEnglish (US)
Pages (from-to)15-21
Number of pages7
JournalMolecular Microbiology
Issue number1
StatePublished - Jul 2010


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