Bacterial characteristics as predictors of posttherapy recurrent bacteriuria among children with acute uncomplicated cystitis caused by Escherichia coli

James R. Johnson, Brian Johnston, Andrew Murray, Michael A. Kuskowski, Joel N. Maslow, Candice Johnson

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Multiple characteristics of pretherapy Escherichia coli urine isolates from 39 children with acute, uncomplicated cystitis (including specific virulence genes and phylogenetic groups) identified an increased risk for recurrent bacteriuria after 3-day (but not 10-day) therapy with amoxicillin-clavulanate. Rapid testing conceivably could facilitate rational selection of treatment duration for pediatric cystitis. Certain traits might represent good targets for preventive interventions.

Original languageEnglish (US)
Pages (from-to)1151-1153
Number of pages3
JournalPediatric Infectious Disease Journal
Volume26
Issue number12
DOIs
StatePublished - Dec 2007

Bibliographical note

Funding Information:
Supported by Office of Research and Development, Medical Research Service, Department of Veterans Affairs (to J. R. J. and J. N. M.), and by grants from the National Institutes of Health (to J. R. J.).

Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.

Keywords

  • Escherichia coli infections
  • Phylogenetics
  • Polymerase chain reaction
  • Urinary tract infection
  • Virulence

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