DIE METABOLISCHE EFFEKTIVITAT HOCHGEREINIGTER AUTOTRANSPLANTIERTER LANGERHANSSCHER INSELN

Translated title of the contribution: Autotransplantation of pancreatic islets

U. J. Hesse, B. J. Hering, R. G. Bretzel, K. Federlin, A. Elewaut, B. De Hemptinne

Research output: Contribution to journalArticlepeer-review

Abstract

Autotransplantation of about 363000 pancreatic islets (i.e. ± 7000/kg body weight) were sufficient to establish a stable normoglycemic metabolic state in a patient with diabetes mellitus. Standardized methods for islet isolation, quality control and transplantation were applied. Despite a reduction in C-peptide levels up to 60% following glucagon stimulation normoglycemia could be sustained without the need of exogenous insulin.

Translated title of the contributionAutotransplantation of pancreatic islets
Original languageGerman
Pages (from-to)62-64
Number of pages3
JournalTransplantationsmedizin: Organ der Deutschen Transplantationsgesellschaft
Volume7
Issue number1
StatePublished - Jan 1 1995

Keywords

  • autotransplantation
  • diabetes mellitus
  • pancreatic islets

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