Autoregulation of iclR, the gene encoding the repressor of the glyoxylate bypass operon

Lizhen Gui, Alden Sunnarborg, Bin Pan, David C. Laporte

Research output: Contribution to journalArticlepeer-review

46 Scopus citations

Abstract

The aceBAK operon was partially induced by a multicopy plasmid which carried the promoter region of the gene which encodes its repressor, iclR. Gel shift and DNase I analyses demonstrated that iclR binds to its own promoter. Disruption of iclR increased the expression of an iclR::lacZ operon fusion. Although aceBAK and iclR are both regulated by IclR, aceBAK expression responds to the carbon source, while expression of iclR does not.

Original languageEnglish (US)
Pages (from-to)321-324
Number of pages4
JournalJournal of bacteriology
Volume178
Issue number1
DOIs
StatePublished - Jan 1996

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