Autonomous immunity in mucosal epithelial cells: fortifying the barrier against infection

Karen F. Ross; Mark C. Herzberg

doi:10.1016/j.micinf.2016.03.008

Autonomous immunity in mucosal epithelial cells: fortifying the barrier against infection

Karen F. Ross, Mark C. Herzberg

Basic Sciences

Research output: Contribution to journal › Short survey › peer-review

19 Scopus citations

Abstract

Mucosal epithelial cells express an autonomous innate immune response that controls the overgrowth of invaded bacteria, mitigates the harmful effects of the bacteria carried within, and does not rely on other external arms of the immune response. Epithelial cell autonomous innate immunity “respects” the social biology of invading bacteria to achieve symbiosis, and is the primary protective mechanism against pathogens.

Original language	English (US)
Pages (from-to)	387-398
Number of pages	12
Journal	Microbes and Infection
Volume	18
Issue number	6
DOIs	https://doi.org/10.1016/j.micinf.2016.03.008
State	Published - Jun 1 2016

Bibliographical note

Publisher Copyright:
© 2016

Keywords

Antimicrobial proteins
Cell signaling
Infection
Innate immunity
Mucosal epithelium

Publisher link

10.1016/j.micinf.2016.03.008

http://europepmc.org/articles/pmc4884473

Find It

Find It at U of M Libraries

Cite this

@article{617493c90184476eb0892fcb6f001efa,

title = "Autonomous immunity in mucosal epithelial cells: fortifying the barrier against infection",

abstract = "Mucosal epithelial cells express an autonomous innate immune response that controls the overgrowth of invaded bacteria, mitigates the harmful effects of the bacteria carried within, and does not rely on other external arms of the immune response. Epithelial cell autonomous innate immunity “respects” the social biology of invading bacteria to achieve symbiosis, and is the primary protective mechanism against pathogens.",

keywords = "Antimicrobial proteins, Cell signaling, Infection, Innate immunity, Mucosal epithelium",

author = "Ross, {Karen F.} and Herzberg, {Mark C.}",

note = "Publisher Copyright: {\textcopyright} 2016",

year = "2016",

month = jun,

day = "1",

doi = "10.1016/j.micinf.2016.03.008",

language = "English (US)",

volume = "18",

pages = "387--398",

journal = "Microbes and Infection",

issn = "1286-4579",

publisher = "Elsevier Masson SAS",

number = "6",

}

TY - JOUR

T1 - Autonomous immunity in mucosal epithelial cells

T2 - fortifying the barrier against infection

AU - Ross, Karen F.

AU - Herzberg, Mark C.

PY - 2016/6/1

Y1 - 2016/6/1

N2 - Mucosal epithelial cells express an autonomous innate immune response that controls the overgrowth of invaded bacteria, mitigates the harmful effects of the bacteria carried within, and does not rely on other external arms of the immune response. Epithelial cell autonomous innate immunity “respects” the social biology of invading bacteria to achieve symbiosis, and is the primary protective mechanism against pathogens.

AB - Mucosal epithelial cells express an autonomous innate immune response that controls the overgrowth of invaded bacteria, mitigates the harmful effects of the bacteria carried within, and does not rely on other external arms of the immune response. Epithelial cell autonomous innate immunity “respects” the social biology of invading bacteria to achieve symbiosis, and is the primary protective mechanism against pathogens.

KW - Antimicrobial proteins

KW - Cell signaling

KW - Infection

KW - Innate immunity

KW - Mucosal epithelium

UR - http://www.scopus.com/inward/record.url?scp=84961864477&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84961864477&partnerID=8YFLogxK

U2 - 10.1016/j.micinf.2016.03.008

DO - 10.1016/j.micinf.2016.03.008

M3 - Short survey

C2 - 27005450

AN - SCOPUS:84961864477

SN - 1286-4579

VL - 18

SP - 387

EP - 398

JO - Microbes and Infection

JF - Microbes and Infection

IS - 6

ER -

Autonomous immunity in mucosal epithelial cells: fortifying the barrier against infection

Abstract

Bibliographical note

Keywords

Publisher link

Find It

Other files and links

Fingerprint

Cite this