Autonomic dysreflexia in a paraplegic man with catecholamine-secreting neuroblastoma

Kenneth C. Wright, James C Agre, Bruce C. Wilson, Athanasios Theologides

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Autonomic dysreflexia and catecholamine secreting tumor, each of which causes paroxysmal hypertension, coexisted in a young man. Two years after neuroblastoma was diagnosed, he developed T4 incomplete paraplegia due to metastases to the spine at T5 and L3 levels. Shortly after the onset of paraplegia, paroxysmal hypertension developed. The hypertension was controlled adequately by good bowel and bladder management and oral clonidine. The paroxysmal hypertension is believed to have resulted from the synergistic effect of the high levels of circulating catecholamines from the tumor and the disruption of autonomic pathways.

Original languageEnglish (US)
Pages (from-to)566-567
Number of pages2
JournalArchives of Physical Medicine and Rehabilitation
Issue number8
StatePublished - Aug 1986


  • Catecholamines
  • Clonidine
  • Neuroblastoma
  • Paraplegia


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