Abstract
An automated instrument was designed and constructed to facilitate the performance of pharmaceutical degradation studies. A brief theoretical background on degradation kinetics is given to rationalize the design of the instrument and representative data are provided to illustrate its successful application. This system was found to be capable of conducting multiple simultaneous isothermal and nonisothermal kinetic studies with user-defined temperature profiles, sampling periods, and data logging.
Original language | English (US) |
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Pages (from-to) | 83-88 |
Number of pages | 6 |
Journal | JALA - Journal of the Association for Laboratory Automation |
Volume | 7 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1 2002 |
Keywords
- Accelerated degradation studies
- Chemical kinetics
- Chemical kinetics instrumentation
- Laboratory automation
- Robotics workstation(s)