Automation of chemical reaction kinetics and product distribution studies in pharmaceutical development

Adam M. Fermier, Alan R. Oyler, Barbara L. Armstrong, Bruce A. Weber, Ramón L. Rodríguez, James V. Weber, James A. Nalasco

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

An automated instrument was designed and constructed to facilitate the performance of pharmaceutical degradation studies. A brief theoretical background on degradation kinetics is given to rationalize the design of the instrument and representative data are provided to illustrate its successful application. This system was found to be capable of conducting multiple simultaneous isothermal and nonisothermal kinetic studies with user-defined temperature profiles, sampling periods, and data logging.

Original languageEnglish (US)
Pages (from-to)83-88
Number of pages6
JournalJALA - Journal of the Association for Laboratory Automation
Volume7
Issue number1
DOIs
StatePublished - Jan 1 2002

Keywords

  • Accelerated degradation studies
  • Chemical kinetics
  • Chemical kinetics instrumentation
  • Laboratory automation
  • Robotics workstation(s)

Fingerprint Dive into the research topics of 'Automation of chemical reaction kinetics and product distribution studies in pharmaceutical development'. Together they form a unique fingerprint.

Cite this