Autoimmune thrombocytopenia in a patient with small cell lung cancer developing after chemotherapy and resolving following autologous peripheral blood stem cell transplantation

T. Demirer; H. Çelebi; M. Arat; C. Üstün; S. Demirer; I. Dilek; M. Özcan; O. Ilhan; H. Akan; G. Gürman; H. Koç

doi:10.1038/sj.bmt.1701902

Autoimmune thrombocytopenia in a patient with small cell lung cancer developing after chemotherapy and resolving following autologous peripheral blood stem cell transplantation

T. Demirer, H. Çelebi, M. Arat, C. Üstün, S. Demirer, I. Dilek, M. Özcan, O. Ilhan, H. Akan, G. Gürman, H. Koç

Medicine - Hematology, Oncology, Transplant

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

A 46-year-old white male with small cell lung cancer (SCLC) limited to the thorax developed autoimmune thrombocytopenic purpura (AITP), following a cyclophosphamide, paclitaxel and G-CSF-containing regimen for peripheral blood stem cell (PBSC) mobilization. AITP associated with small or non-small cell lung cancer has been reported. We considered that the AITP in this case may be a part of paraneoplastic syndrome, which is frequently seen in patients with SCLC. The patient received HDC and autologous PBSC transplantation (APBSCT) for SCLC and the AITP resolved following transplantation, thus supporting the concept of HDC + APBSCT for the treatment of autoimmune diseases.

Original language	English (US)
Pages (from-to)	335-337
Number of pages	3
Journal	Bone marrow transplantation
Volume	24
Issue number	3
DOIs	https://doi.org/10.1038/sj.bmt.1701902
State	Published - 1999

Keywords

Autoimmune thrombocytopenia
Autologous peripheral blood stem cell transplantation
Small cell lung cancer

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/sj.bmt.1701902

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Demirer, T., Çelebi, H., Arat, M., Üstün, C., Demirer, S., Dilek, I., Özcan, M., Ilhan, O., Akan, H., Gürman, G., & Koç, H. (1999). Autoimmune thrombocytopenia in a patient with small cell lung cancer developing after chemotherapy and resolving following autologous peripheral blood stem cell transplantation. Bone marrow transplantation, 24(3), 335-337. https://doi.org/10.1038/sj.bmt.1701902

Demirer, T, Çelebi, H, Arat, M, Üstün, C, Demirer, S, Dilek, I, Özcan, M, Ilhan, O, Akan, H, Gürman, G & Koç, H 1999, 'Autoimmune thrombocytopenia in a patient with small cell lung cancer developing after chemotherapy and resolving following autologous peripheral blood stem cell transplantation', Bone marrow transplantation, vol. 24, no. 3, pp. 335-337. https://doi.org/10.1038/sj.bmt.1701902

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title = "Autoimmune thrombocytopenia in a patient with small cell lung cancer developing after chemotherapy and resolving following autologous peripheral blood stem cell transplantation",

abstract = "A 46-year-old white male with small cell lung cancer (SCLC) limited to the thorax developed autoimmune thrombocytopenic purpura (AITP), following a cyclophosphamide, paclitaxel and G-CSF-containing regimen for peripheral blood stem cell (PBSC) mobilization. AITP associated with small or non-small cell lung cancer has been reported. We considered that the AITP in this case may be a part of paraneoplastic syndrome, which is frequently seen in patients with SCLC. The patient received HDC and autologous PBSC transplantation (APBSCT) for SCLC and the AITP resolved following transplantation, thus supporting the concept of HDC + APBSCT for the treatment of autoimmune diseases.",

keywords = "Autoimmune thrombocytopenia, Autologous peripheral blood stem cell transplantation, Small cell lung cancer",

author = "T. Demirer and H. {\c C}elebi and M. Arat and C. {\"U}st{\"u}n and S. Demirer and I. Dilek and M. {\"O}zcan and O. Ilhan and H. Akan and G. G{\"u}rman and H. Ko{\c c}",

year = "1999",

doi = "10.1038/sj.bmt.1701902",

language = "English (US)",

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pages = "335--337",

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T1 - Autoimmune thrombocytopenia in a patient with small cell lung cancer developing after chemotherapy and resolving following autologous peripheral blood stem cell transplantation

AU - Demirer, T.

AU - Çelebi, H.

AU - Arat, M.

AU - Üstün, C.

AU - Demirer, S.

AU - Dilek, I.

AU - Özcan, M.

AU - Ilhan, O.

AU - Akan, H.

AU - Gürman, G.

AU - Koç, H.

PY - 1999

Y1 - 1999

N2 - A 46-year-old white male with small cell lung cancer (SCLC) limited to the thorax developed autoimmune thrombocytopenic purpura (AITP), following a cyclophosphamide, paclitaxel and G-CSF-containing regimen for peripheral blood stem cell (PBSC) mobilization. AITP associated with small or non-small cell lung cancer has been reported. We considered that the AITP in this case may be a part of paraneoplastic syndrome, which is frequently seen in patients with SCLC. The patient received HDC and autologous PBSC transplantation (APBSCT) for SCLC and the AITP resolved following transplantation, thus supporting the concept of HDC + APBSCT for the treatment of autoimmune diseases.

AB - A 46-year-old white male with small cell lung cancer (SCLC) limited to the thorax developed autoimmune thrombocytopenic purpura (AITP), following a cyclophosphamide, paclitaxel and G-CSF-containing regimen for peripheral blood stem cell (PBSC) mobilization. AITP associated with small or non-small cell lung cancer has been reported. We considered that the AITP in this case may be a part of paraneoplastic syndrome, which is frequently seen in patients with SCLC. The patient received HDC and autologous PBSC transplantation (APBSCT) for SCLC and the AITP resolved following transplantation, thus supporting the concept of HDC + APBSCT for the treatment of autoimmune diseases.

KW - Autoimmune thrombocytopenia

KW - Autologous peripheral blood stem cell transplantation

KW - Small cell lung cancer

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JF - Bone marrow transplantation

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ER -

Autoimmune thrombocytopenia in a patient with small cell lung cancer developing after chemotherapy and resolving following autologous peripheral blood stem cell transplantation

Abstract

Keywords

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