Autoimmune granulocytopenia occurs as an isolated problem in children and is a common part of many autoimmune diseases in adults and children. Although the exact cause of primary AIG is not known, the granulocytopenia is due to accelerated destruction of mature granulocytes in the peripheral circulation. Granulocyte antibody studies are helfpul in identifying these patients. In children the disese is self-limited, and in most patients treatment of infections is all that is required. The course and management of patients with secondary AIG should focus on the underlying disease.
|Original language||English (US)|
|Number of pages||24|
|Journal||Bailliere's Clinical Immunology and Allergy|
|State||Published - Jan 1 1987|