Tested and confirmed the hypothesis that scopolamine attenuates habituation occurring within a training session as well as that occurring between training sessions. Subcutaneous scopolamine injections (.5 mg/kg) reduced spontaneous wheel running in 8 female prairie dogs. The same dosage did not affect the threshold for wheel running induced by electrical brain stimulation (EBS) in 6 Ss in Exp II. Exp III (n = 6) demonstrated that EBS-induced running declined during a 10-min stimulation period and indicated that the decline was habituative since the response was repeatedly dishabituated. In Exp IV .5 mg/kg of scopolamine reduced habituation of EBS-induced wheel running during 10-min sessions with the 6 Ss used in Exp II. (22 ref) (PsycINFO Database Record (c) 2006 APA, all rights reserved).
|Original language||English (US)|
|Number of pages||7|
|Journal||Journal of Comparative and Physiological Psychology|
|State||Published - Jan 1 1975|
- scopolamine, attenuation of acute habituation, prairie dogs