Attenuation of "acute" habituation by scopolamine in the black-tailed prairie dog (Cynomys ludovicianus)

R. H. Carlson; M. G. Sanders; A. Tal; W. Gibson Wood

doi:10.1037/h0076205

Attenuation of "acute" habituation by scopolamine in the black-tailed prairie dog (Cynomys ludovicianus)

R. H. Carlson, M. G. Sanders, A. Tal, W. Gibson Wood

Pharmacology

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4 Scopus citations

Abstract

Tested and confirmed the hypothesis that scopolamine attenuates habituation occurring within a training session as well as that occurring between training sessions. Subcutaneous scopolamine injections (.5 mg/kg) reduced spontaneous wheel running in 8 female prairie dogs. The same dosage did not affect the threshold for wheel running induced by electrical brain stimulation (EBS) in 6 Ss in Exp II. Exp III (n = 6) demonstrated that EBS-induced running declined during a 10-min stimulation period and indicated that the decline was habituative since the response was repeatedly dishabituated. In Exp IV .5 mg/kg of scopolamine reduced habituation of EBS-induced wheel running during 10-min sessions with the 6 Ss used in Exp II. (22 ref) (PsycINFO Database Record (c) 2006 APA, all rights reserved).

Original language	English (US)
Pages (from-to)	335-341
Number of pages	7
Journal	Journal of Comparative and Physiological Psychology
Volume	88
Issue number	1
DOIs	https://doi.org/10.1037/h0076205
State	Published - Jan 1975

Keywords

scopolamine, attenuation of acute habituation, prairie dogs

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10.1037/h0076205

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AU - Tal, A.

AU - Wood, W. Gibson

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AB - Tested and confirmed the hypothesis that scopolamine attenuates habituation occurring within a training session as well as that occurring between training sessions. Subcutaneous scopolamine injections (.5 mg/kg) reduced spontaneous wheel running in 8 female prairie dogs. The same dosage did not affect the threshold for wheel running induced by electrical brain stimulation (EBS) in 6 Ss in Exp II. Exp III (n = 6) demonstrated that EBS-induced running declined during a 10-min stimulation period and indicated that the decline was habituative since the response was repeatedly dishabituated. In Exp IV .5 mg/kg of scopolamine reduced habituation of EBS-induced wheel running during 10-min sessions with the 6 Ss used in Exp II. (22 ref) (PsycINFO Database Record (c) 2006 APA, all rights reserved).

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Attenuation of "acute" habituation by scopolamine in the black-tailed prairie dog (Cynomys ludovicianus)

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