Atrial fibrillation susceptibility in metabolic syndrome: Simply the sum of its parts?

John T. Nguyen, David G Benditt

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


The report by Watanabe et al in this issue of Circulation provides support for the view that MS increases susceptibility to AF. Whether the increased AF risk in MS patients is due to the syndrome as a whole or simply the sum of the risks of its individual component parts is perhaps not unequivocally settled. Nevertheless, the observations of Watanabe et al, in conjunction with the disturbingly high prevalence of MS in the general population (≈20% in the United States), highlight an underappreciated but important adverse MS health risk, namely increased AF susceptibility. Furthermore, given the mounting evidence, it seems increasingly clear that physicians must, in their AF prevention and treatment strategies, focus aggressively on addressing blood pressure control, diabetes and glucose intolerance management, weight reduction, and the recognition and treatment of obstructive sleep apnea.

Original languageEnglish (US)
Pages (from-to)1249-1251
Number of pages3
Issue number10
StatePublished - Mar 2008


  • Arrhythmia
  • Atrial fibrillation
  • Editorials
  • Electrocardiography
  • Metabolic syndrome X
  • Metabolism


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