Atrial arrhythmias after lung transplantation

Research output: Contribution to journalReview article

5 Citations (Scopus)

Abstract

Atrial arrhythmias are a common complication after lung transplant (LT), occurring in about 16–46% of LT patients early postoperatively, and in about 14% during longer-term follow-up. They have a significant impact on postoperative in-hospital length of stay and may have an impact on overall mortality. In this report, we review the incidence and risk factors of post lung transplant AA, their pathogenesis and their impact on short- and long-term outcomes. Pharmacological management options are reviewed. In brief, early atrial arrhythmias tend to be mostly atrial fibrillation and are treated acutely with a rate control strategy followed if needed by rhythm control for 4–6 weeks. Late atrial arrhythmias >6 months after LT tend to be more frequently organized atrial flutters amenable to ablation therapy. Long-term anticoagulation is controversial especially in patients with bilateral lung transplant who received surgical pulmonic vein isolation, however anticoagulation is still favored especially in single LT patients. More studies are needed to further document the pathophysiology of early versus late atrial arrhythmias and whether long-term anticoagulation is needed.

Original languageEnglish (US)
Pages (from-to)53-61
Number of pages9
JournalTrends in Cardiovascular Medicine
Volume28
Issue number1
DOIs
StatePublished - Jan 2018

Fingerprint

Lung Transplantation
Cardiac Arrhythmias
Lung
Transplants
Length of Stay
Atrial Flutter
Atrial Fibrillation
Veins
Pharmacology
Mortality
Incidence

Keywords

  • Atrial arrhythmias
  • Atrial fibrillation
  • Lung transplant

Cite this

Atrial arrhythmias after lung transplantation. / Roukoz, Henri; Benditt, David G.

In: Trends in Cardiovascular Medicine, Vol. 28, No. 1, 01.2018, p. 53-61.

Research output: Contribution to journalReview article

@article{55b7b478d15240c48c46aa7a9297dbb5,
title = "Atrial arrhythmias after lung transplantation",
abstract = "Atrial arrhythmias are a common complication after lung transplant (LT), occurring in about 16–46{\%} of LT patients early postoperatively, and in about 14{\%} during longer-term follow-up. They have a significant impact on postoperative in-hospital length of stay and may have an impact on overall mortality. In this report, we review the incidence and risk factors of post lung transplant AA, their pathogenesis and their impact on short- and long-term outcomes. Pharmacological management options are reviewed. In brief, early atrial arrhythmias tend to be mostly atrial fibrillation and are treated acutely with a rate control strategy followed if needed by rhythm control for 4–6 weeks. Late atrial arrhythmias >6 months after LT tend to be more frequently organized atrial flutters amenable to ablation therapy. Long-term anticoagulation is controversial especially in patients with bilateral lung transplant who received surgical pulmonic vein isolation, however anticoagulation is still favored especially in single LT patients. More studies are needed to further document the pathophysiology of early versus late atrial arrhythmias and whether long-term anticoagulation is needed.",
keywords = "Atrial arrhythmias, Atrial fibrillation, Lung transplant",
author = "Henri Roukoz and Benditt, {David G.}",
year = "2018",
month = "1",
doi = "10.1016/j.tcm.2017.07.009",
language = "English (US)",
volume = "28",
pages = "53--61",
journal = "Trends in Cardiovascular Medicine",
issn = "1050-1738",
publisher = "Elsevier Inc.",
number = "1",

}

TY - JOUR

T1 - Atrial arrhythmias after lung transplantation

AU - Roukoz, Henri

AU - Benditt, David G.

PY - 2018/1

Y1 - 2018/1

N2 - Atrial arrhythmias are a common complication after lung transplant (LT), occurring in about 16–46% of LT patients early postoperatively, and in about 14% during longer-term follow-up. They have a significant impact on postoperative in-hospital length of stay and may have an impact on overall mortality. In this report, we review the incidence and risk factors of post lung transplant AA, their pathogenesis and their impact on short- and long-term outcomes. Pharmacological management options are reviewed. In brief, early atrial arrhythmias tend to be mostly atrial fibrillation and are treated acutely with a rate control strategy followed if needed by rhythm control for 4–6 weeks. Late atrial arrhythmias >6 months after LT tend to be more frequently organized atrial flutters amenable to ablation therapy. Long-term anticoagulation is controversial especially in patients with bilateral lung transplant who received surgical pulmonic vein isolation, however anticoagulation is still favored especially in single LT patients. More studies are needed to further document the pathophysiology of early versus late atrial arrhythmias and whether long-term anticoagulation is needed.

AB - Atrial arrhythmias are a common complication after lung transplant (LT), occurring in about 16–46% of LT patients early postoperatively, and in about 14% during longer-term follow-up. They have a significant impact on postoperative in-hospital length of stay and may have an impact on overall mortality. In this report, we review the incidence and risk factors of post lung transplant AA, their pathogenesis and their impact on short- and long-term outcomes. Pharmacological management options are reviewed. In brief, early atrial arrhythmias tend to be mostly atrial fibrillation and are treated acutely with a rate control strategy followed if needed by rhythm control for 4–6 weeks. Late atrial arrhythmias >6 months after LT tend to be more frequently organized atrial flutters amenable to ablation therapy. Long-term anticoagulation is controversial especially in patients with bilateral lung transplant who received surgical pulmonic vein isolation, however anticoagulation is still favored especially in single LT patients. More studies are needed to further document the pathophysiology of early versus late atrial arrhythmias and whether long-term anticoagulation is needed.

KW - Atrial arrhythmias

KW - Atrial fibrillation

KW - Lung transplant

UR - http://www.scopus.com/inward/record.url?scp=85026828151&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85026828151&partnerID=8YFLogxK

U2 - 10.1016/j.tcm.2017.07.009

DO - 10.1016/j.tcm.2017.07.009

M3 - Review article

C2 - 28797718

AN - SCOPUS:85026828151

VL - 28

SP - 53

EP - 61

JO - Trends in Cardiovascular Medicine

JF - Trends in Cardiovascular Medicine

SN - 1050-1738

IS - 1

ER -