Atopic eczema unresponsive to evening primrose oil (linoleic and γ-linolenic acids)

J. T M Bamford, R. W. Gibson, C. M. Renier

Research output: Contribution to journalArticlepeer-review

94 Scopus citations

Abstract

This study was designed to look at the effect of evening primrose oil (linoleic and γ-linolenic acids) as an oral supplement for patients with atopic eczema. We used a double-blind, blocked crossover design with random assignment of patients to treatment groups. We used Wilcoxon's signed-ranks method of comparing changes during the trial. We observed no significant effect on erythema, scale, excoriation, lichenification, or overall severity in 123 patients with atopic eczema of average severity while they took oral doses of evening primrose oil (2 or 4 gm in children, 6 or 8 gm in adults).

Original languageEnglish (US)
Pages (from-to)959-965
Number of pages7
JournalJournal of the American Academy of Dermatology
Volume13
Issue number6
StatePublished - 1985

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