At the frontiers of surgery: Review

Tahwinder Upile, Waseem K. Jerjes, Henricus J. Sterenborg, Brian J. Wong, Adel K. El-Naggar, Justus F. Ilgner, Ann Sandison, Max J. Witjes, Merrill A. Biel, Robert Van Veen, Zaid Hamdoon, Ann Gillenwater, Charles A. Mosse, Dominic J. Robinson, Christian S. Betz, Herbert Stepp, Lina Bolotine, Gordon McKenzie, Hugh Barr, Zhongping ChenKristian Berg, Anil K. D'Cruz, Holger Sudhoff, Nicholas Stone, Catherine Kendall, Sheila Fisher, Alexander J. MacRobert, Andreas Leunig, Malini Olivo, Rebecca Richards-Kortum, Khee C. Soo, Vanderlei Bagnato, Lin Ping Choo-Smith, Katarina Svanberg, I. Bing Tan, Brian C. Wilson, Herbert Wolfsen, Irving Bigio, Arjun G. Yodh, Colin Hopper

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


The complete surgical removal of disease is a desirable outcome particularly in oncology. Unfortunately much disease is microscopic and difficult to detect causing a liability to recurrence and worsened overall prognosis with attendant costs in terms of morbidity and mortality. It is hoped that by advances in optical diagnostic technology we could better define our surgical margin and so increase the rate of truly negative margins on the one hand and on the other hand to take out only the necessary amount of tissue and leave more unaffected non-diseased areas so preserving function of vital structures. The task has not been easy but progress is being made as exemplified by the presentations at the 2nd Scientific Meeting of the Head and Neck Optical Diagnostics Society (HNODS) in San Francisco in January 2010. We review the salient advances in the field and propose further directions of investigation.

Original languageEnglish (US)
Article number7
JournalHead and Neck Oncology
Issue number1
StatePublished - 2011


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