(equation presented) This first asymmetric synthesis of enantiopure desacetylumuravumbolide and umuravumbolide via asymmetric reduction, allylboration, and ring-closing metathesis confirms their revised structures and configurations. A convenient procedure to upgrade the enantiopurity of α,β-acetylenic alcohols is also described.
|Original language||English (US)|
|Number of pages||2|
|State||Published - Jan 11 2001|