Abstract
An efficient asymmetric synthesis of (+)-tetrahydropseudodistomin is described. The important synthetic features include a Maruoka asymmetric allylation and a Sharpless asymmetric dihydroxylation as key steps for the generation of chirality at C-2, -4, and -5 of the trisubstituted piperidine ring.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 2373-2375 |
| Number of pages | 3 |
| Journal | Tetrahedron Letters |
| Volume | 48 |
| Issue number | 13 |
| DOIs | |
| State | Published - Mar 26 2007 |
| Externally published | Yes |
Bibliographical note
Funding Information:S.S.S. thanks the CSIR, New Delhi and N.K. thanks the UGC, New Delhi, for financial support and S.C. thanks the DST, New Delhi, for a grant.
Keywords
- Marouka asymmetric allylation
- Sharpless asymmetric dihydroxylation
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