Asymmetric synthesis of α-alkylated α-amino acids: azepane-2-carboxylic acids

Gunda I. Georg, Xiangming Guan, Joydeep Kant

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

The synthesis of optically active α-alkylated azepane-2-carboxylic acid esters 3 was achieved via Schmidt rearrangement of optically active ethyl 2-oxo-1-alkyl-cyclohexanecarboxylates 1 followed by selective reduction of the amide carbonyl group.

Original languageEnglish (US)
Pages (from-to)125-128
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume1
Issue number2
DOIs
StatePublished - 1991

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