Asymmetric N-heterocyclic carbene (NHC)-catalyzed annulation of modified enals with enolizable aldehydes

Santhivardhana Reddy Yetra; Trinadh Kaicharla; Sunita S. Kunte; Rajesh G. Gonnade; Akkattu T. Biju

doi:10.1021/ol4026155

Asymmetric N-heterocyclic carbene (NHC)-catalyzed annulation of modified enals with enolizable aldehydes

Santhivardhana Reddy Yetra
, Trinadh Kaicharla
, Sunita S. Kunte
, Rajesh G. Gonnade
, Akkattu T. Biju

Research output: Contribution to journal › Article › peer-review

93 Scopus citations

Abstract

N-Heterocyclic carbene (NHC)-catalyzed highly enantioselective lactonization of modified enals with enolizable aldehydes, proceeding via the α,β-unsaturated acylazolium intermediates, is reported. The reaction results in the asymmetric synthesis of synthetically important 4,5-disubstituted dihydropyranones.

Original language	English (US)
Pages (from-to)	5202-5205
Number of pages	4
Journal	Organic Letters
Volume	15
Issue number	20
DOIs	https://doi.org/10.1021/ol4026155
State	Published - Oct 18 2013
Externally published	Yes

Publisher link

10.1021/ol4026155

Find It

Find It at U of M Libraries

Cite this

@article{400427a89f14484899df716e1784b457,

title = "Asymmetric N-heterocyclic carbene (NHC)-catalyzed annulation of modified enals with enolizable aldehydes",

abstract = "N-Heterocyclic carbene (NHC)-catalyzed highly enantioselective lactonization of modified enals with enolizable aldehydes, proceeding via the α,β-unsaturated acylazolium intermediates, is reported. The reaction results in the asymmetric synthesis of synthetically important 4,5-disubstituted dihydropyranones.",

author = "Yetra, \{Santhivardhana Reddy\} and Trinadh Kaicharla and Kunte, \{Sunita S.\} and Gonnade, \{Rajesh G.\} and Biju, \{Akkattu T.\}",

year = "2013",

month = oct,

day = "18",

doi = "10.1021/ol4026155",

language = "English (US)",

volume = "15",

pages = "5202--5205",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "20",

}

TY - JOUR

T1 - Asymmetric N-heterocyclic carbene (NHC)-catalyzed annulation of modified enals with enolizable aldehydes

AU - Yetra, Santhivardhana Reddy

AU - Kaicharla, Trinadh

AU - Kunte, Sunita S.

AU - Gonnade, Rajesh G.

AU - Biju, Akkattu T.

PY - 2013/10/18

Y1 - 2013/10/18

N2 - N-Heterocyclic carbene (NHC)-catalyzed highly enantioselective lactonization of modified enals with enolizable aldehydes, proceeding via the α,β-unsaturated acylazolium intermediates, is reported. The reaction results in the asymmetric synthesis of synthetically important 4,5-disubstituted dihydropyranones.

AB - N-Heterocyclic carbene (NHC)-catalyzed highly enantioselective lactonization of modified enals with enolizable aldehydes, proceeding via the α,β-unsaturated acylazolium intermediates, is reported. The reaction results in the asymmetric synthesis of synthetically important 4,5-disubstituted dihydropyranones.

UR - https://www.scopus.com/pages/publications/84886300271

UR - https://www.scopus.com/pages/publications/84886300271#tab=citedBy

U2 - 10.1021/ol4026155

DO - 10.1021/ol4026155

M3 - Article

AN - SCOPUS:84886300271

SN - 1523-7060

VL - 15

SP - 5202

EP - 5205

JO - Organic Letters

JF - Organic Letters

IS - 20

ER -

Asymmetric N-heterocyclic carbene (NHC)-catalyzed annulation of modified enals with enolizable aldehydes

Abstract

Publisher link

Find It

Other files and links

Fingerprint

Cite this