Asymmetric aldol reactions in poly(ethylene glycol) catalyzed by L-proline

S. Chandrasekhar; Ch Narsihmulu; N. Ramakrishna Reddy; S. Shameem Sultana

doi:10.1016/j.tetlet.2004.03.116

Asymmetric aldol reactions in poly(ethylene glycol) catalyzed by L-proline

S. Chandrasekhar, Ch Narsihmulu, N. Ramakrishna Reddy, S. Shameem Sultana

Research output: Contribution to journal › Article › peer-review

96 Scopus citations

Abstract

A rapid L-proline catalyzed direct aldol reaction between various aldehydes and acetone was achieved using PEG as the solvent with comparable enantioselectivities and yields to those obtained in other solvents. Recycling the catalyst and solvent (PEG) was possible 10 times without loss of activity.

Original language	English (US)
Pages (from-to)	4581-4582
Number of pages	2
Journal	Tetrahedron Letters
Volume	45
Issue number	23
DOIs	https://doi.org/10.1016/j.tetlet.2004.03.116
State	Published - May 31 2004
Externally published	Yes

Bibliographical note

Funding Information:
We C.N., N.R.K. and S.S.S. thank CSIR New Delhi for financial support.

Keywords

Asymmetric aldol reaction
L-Proline
PEG
Reusability

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10.1016/j.tetlet.2004.03.116

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abstract = "A rapid L-proline catalyzed direct aldol reaction between various aldehydes and acetone was achieved using PEG as the solvent with comparable enantioselectivities and yields to those obtained in other solvents. Recycling the catalyst and solvent (PEG) was possible 10 times without loss of activity.",

keywords = "Asymmetric aldol reaction, L-Proline, PEG, Reusability",

author = "S. Chandrasekhar and Ch Narsihmulu and Reddy, {N. Ramakrishna} and Sultana, {S. Shameem}",

note = "Funding Information: We C.N., N.R.K. and S.S.S. thank CSIR New Delhi for financial support.",

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T1 - Asymmetric aldol reactions in poly(ethylene glycol) catalyzed by L-proline

AU - Chandrasekhar, S.

AU - Narsihmulu, Ch

AU - Reddy, N. Ramakrishna

AU - Sultana, S. Shameem

N1 - Funding Information: We C.N., N.R.K. and S.S.S. thank CSIR New Delhi for financial support.

PY - 2004/5/31

Y1 - 2004/5/31

N2 - A rapid L-proline catalyzed direct aldol reaction between various aldehydes and acetone was achieved using PEG as the solvent with comparable enantioselectivities and yields to those obtained in other solvents. Recycling the catalyst and solvent (PEG) was possible 10 times without loss of activity.

AB - A rapid L-proline catalyzed direct aldol reaction between various aldehydes and acetone was achieved using PEG as the solvent with comparable enantioselectivities and yields to those obtained in other solvents. Recycling the catalyst and solvent (PEG) was possible 10 times without loss of activity.

KW - Asymmetric aldol reaction

KW - L-Proline

KW - PEG

KW - Reusability

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 23

ER -

Asymmetric aldol reactions in poly(ethylene glycol) catalyzed by L-proline

Abstract

Bibliographical note

Keywords

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