TY - JOUR
T1 - Astroblastoma and other predominantly pediatric supratentorial papillary/epithelioid gliomas
AU - El Hag, Mohamed I.A.
AU - Hdeib, Alia
AU - Ciarlini, Pedro D.S.C.
AU - Cohen, Mark L.
PY - 2013/12/1
Y1 - 2013/12/1
N2 - Astroblastomas are rare primary brain tumors with no currently assigned World Health Organization grade. In their classical presentation, they are well-circumscribed supratentorial solid-cystic tumors with minimal peritumoral T2 hyperintensity. They can be difficult to distinguish from other predominantly pediatric supratentorial papillary/epithelioid gliomas, such as ependymomas, choroid plexus tumors, papillary glioneuronal tumors, papillary tumors of the pineal region, and occasionally atypical teratoid/rhabdoid tumor of the central nervous system. Distinct morphologic, immunohistochemical, and ultrastructural features aid in reaching a definitive diagnosis. In this review, we present a case of pediatric astroblastoma with a unique course and discuss the key differences and similarities between astroblastomas and other predominantly pediatric supratentorial papillary/epithelioid gliomas.
AB - Astroblastomas are rare primary brain tumors with no currently assigned World Health Organization grade. In their classical presentation, they are well-circumscribed supratentorial solid-cystic tumors with minimal peritumoral T2 hyperintensity. They can be difficult to distinguish from other predominantly pediatric supratentorial papillary/epithelioid gliomas, such as ependymomas, choroid plexus tumors, papillary glioneuronal tumors, papillary tumors of the pineal region, and occasionally atypical teratoid/rhabdoid tumor of the central nervous system. Distinct morphologic, immunohistochemical, and ultrastructural features aid in reaching a definitive diagnosis. In this review, we present a case of pediatric astroblastoma with a unique course and discuss the key differences and similarities between astroblastomas and other predominantly pediatric supratentorial papillary/epithelioid gliomas.
KW - Astroblastoma
KW - Pediatric gliomas
KW - Supratentorial papillary/epithelioid glioma
UR - http://www.scopus.com/inward/record.url?scp=84892750118&partnerID=8YFLogxK
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U2 - 10.1097/PCR.0000000000000010
DO - 10.1097/PCR.0000000000000010
M3 - Review article
AN - SCOPUS:84892750118
VL - 18
SP - 244
EP - 252
JO - Pathology Case Reviews
JF - Pathology Case Reviews
SN - 1082-9784
IS - 6
ER -