Associations between medical history, cognition, and behavior in youth with down syndrome: A report from the down syndrome cognition project

Tracie C. Rosser; Jamie O. Edgin; George T. Capone; Debra R. Hamilton; Emily G. Allen; Kenneth J. Dooley; Payal Anand; John F. Strang; A. Chelsea Armour; Michelle A. Frank-Crawford; Marie Moore Channell; Elizabeth I. Pierpont; Eleanor Feingold; Cheryl L. Maslen; Roger H. Reeves; Stephanie L. Sherman

doi:10.1352/1944-7558-123.6.514

Associations between medical history, cognition, and behavior in youth with down syndrome: A report from the down syndrome cognition project

Tracie C. Rosser, Jamie O. Edgin, George T. Capone, Debra R. Hamilton, Emily G. Allen, Kenneth J. Dooley, Payal Anand, John F. Strang, A. Chelsea Armour, Michelle A. Frank-Crawford, Marie Moore Channell, Elizabeth I. Pierpont, Eleanor Feingold, Cheryl L. Maslen, Roger H. Reeves, Stephanie L. Sherman

Clinical Behavioral Neuroscience (Pediatrics)

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

The cause of the high degree of variability in cognition and behavior among individuals with Down syndrome (DS) is unknown. We hypothesized that birth defects requiring surgery in the first years of life (congenital heart defects and gastrointestinal defects) might affect an individual's level of function. We used data from the first 234 individuals, age 6-25 years, enrolled in the Down Syndrome Cognition Project (DSCP) to test this hypothesis. Data were drawn from medical records, parent interviews, and a cognitive and behavior assessment battery. Results did not support our hypothesis. That is, we found no evidence that either birth defect was associated with poorer outcomes, adjusting for gender, race/ethnicity, and socioeconomic status. Implications for study design and measurement are discussed.

Original language	English (US)
Pages (from-to)	514-528
Number of pages	15
Journal	American journal on intellectual and developmental disabilities
Volume	123
Issue number	6
DOIs	https://doi.org/10.1352/1944-7558-123.6.514
State	Published - Nov 2018

Bibliographical note

Publisher Copyright:
© AAIDD.

Keywords

Behavior
Birth defect
Cognition
Congenital heart defect
Down syndrome
Gastrointestinal defect
Intellectual disability
Neuropsychological assessment
Trisomy 21

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Rosser, T. C., Edgin, J. O., Capone, G. T., Hamilton, D. R., Allen, E. G., Dooley, K. J., Anand, P., Strang, J. F., Armour, A. C., Frank-Crawford, M. A., Channell, M. M., Pierpont, E. I., Feingold, E., Maslen, C. L., Reeves, R. H., & Sherman, S. L. (2018). Associations between medical history, cognition, and behavior in youth with down syndrome: A report from the down syndrome cognition project. American journal on intellectual and developmental disabilities, 123(6), 514-528. https://doi.org/10.1352/1944-7558-123.6.514

Associations between medical history, cognition, and behavior in youth with down syndrome: A report from the down syndrome cognition project. / Rosser, Tracie C.; Edgin, Jamie O.; Capone, George T. et al.
In: American journal on intellectual and developmental disabilities, Vol. 123, No. 6, 11.2018, p. 514-528.

Research output: Contribution to journal › Article › peer-review

Rosser, TC, Edgin, JO, Capone, GT, Hamilton, DR, Allen, EG, Dooley, KJ, Anand, P, Strang, JF, Armour, AC, Frank-Crawford, MA, Channell, MM, Pierpont, EI, Feingold, E, Maslen, CL, Reeves, RH & Sherman, SL 2018, 'Associations between medical history, cognition, and behavior in youth with down syndrome: A report from the down syndrome cognition project', American journal on intellectual and developmental disabilities, vol. 123, no. 6, pp. 514-528. https://doi.org/10.1352/1944-7558-123.6.514

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abstract = "The cause of the high degree of variability in cognition and behavior among individuals with Down syndrome (DS) is unknown. We hypothesized that birth defects requiring surgery in the first years of life (congenital heart defects and gastrointestinal defects) might affect an individual's level of function. We used data from the first 234 individuals, age 6-25 years, enrolled in the Down Syndrome Cognition Project (DSCP) to test this hypothesis. Data were drawn from medical records, parent interviews, and a cognitive and behavior assessment battery. Results did not support our hypothesis. That is, we found no evidence that either birth defect was associated with poorer outcomes, adjusting for gender, race/ethnicity, and socioeconomic status. Implications for study design and measurement are discussed.",

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Associations between medical history, cognition, and behavior in youth with down syndrome: A report from the down syndrome cognition project

Abstract

Bibliographical note

Keywords

UN SDGs

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