Association of varicella, myocarditis, and congestive cardiomyopathy

George R. Noren, John D. Tobin, Nancy A. Staley, Richard W. Asinger, Stanley Einzig

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


A retrospective study of children dying with active varicella revealed 11 of 17 cases who had unsuspected interstitial myocarditis at the time of their death. In addition, a prospective study of 6 children, consecutively admitted to the hospital with active varicella, were evaluated for evidence of cardiac dysfunction by echocardiography, ECG, and serum enzyme levels. All 6 children had Reye's syndrome in association with active varicella. Evidence of myocardial involvement, consistent with acute congestive cardiomyopathy, was documented in 4 of the 6 children. This study suggests that the heart is commonly involved in varicella infections and that cardiac involvement should be considered in children with this disease.

Original languageEnglish (US)
Pages (from-to)53-57
Number of pages5
JournalPediatric Cardiology
Issue number1
StatePublished - Mar 1 1982


  • Congestive cardiomyopathy
  • Myocarditis
  • Reye's syndrome
  • Varicella


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