Association of household income and adverse outcomes in patients with atrial fibrillation

Anna Rose Larosa, J'Neka Claxton, Wesley T. O'Neal, Pamela L. Lutsey, Lin Y. Chen, Lindsay Bengtson, Alanna M. Chamberlain, Alvaro Alonso, Jared W. Magnani

Research output: Contribution to journalArticle

Abstract

Background: Social determinants of health are relevant to cardiovascular outcomes but have had limited examination in atrial fibrillation (AF). Objectives: The purpose of this study was to examine the association of annual household income and cardiovascular outcomes in individuals with AF. Methods: We analysed administrative claims for individuals with AF from 2009 to 2015 captured by a health claims database. We categorised estimates of annual household income as <$40 000; $40-$59 999; $60-$74 999; $75-$99 999; and ≥$100 000. Covariates included demographics, education, cardiovascular disease risk factors, comorbid conditions and anticoagulation. We examined event rates by income category and in multivariable-adjusted models in reference to the highest income category (≥$100 000). Results: Our analysis included 336 736 individuals (age 72.7±11.9 years; 44.5% women; 82.6% white, 8.4% black, 7.0% Hispanic and 2.1% Asian) with AF followed for median (25th and 75th percentile) of 1.5 (95% CI 0.6 to 3.0) years. We observed an inverse association between income and heart failure and myocardial infarction (MI) with evidence of progressive risk across decreased income categories. Individuals with household income <$40 000 had the greatest risk for heart failure (HR 1.17; 95% CI 1.05 to 1.30) and MI (HR 1.18; 95% CI 0.98 to 1.41) compared with those with income ≥$100 000. Conclusions: We identified an association between lower household income and adverse outcomes in a large cohort of individuals with AF. Our findings support consideration of income in the evaluation of cardiovascular risk in individuals with AF.

Original languageEnglish (US)
Article number316065
JournalHeart
DOIs
StateAccepted/In press - Jan 1 2020

Keywords

  • atrial fibrillation
  • quality and outcomes of care

Fingerprint Dive into the research topics of 'Association of household income and adverse outcomes in patients with atrial fibrillation'. Together they form a unique fingerprint.

  • Cite this

    Larosa, A. R., Claxton, JN., O'Neal, W. T., Lutsey, P. L., Chen, L. Y., Bengtson, L., Chamberlain, A. M., Alonso, A., & Magnani, J. W. (Accepted/In press). Association of household income and adverse outcomes in patients with atrial fibrillation. Heart, [316065]. https://doi.org/10.1136/heartjnl-2019-316065