Association between excessive daytime sleepiness and measures of supraventricular arrhythmia burden: evidence from the Atherosclerosis Risk in Communities (ARIC) study

Kelsie M. Full, Pamela L. Lutsey, Faye L. Norby, Alvaro Alonso, Elsayed Z. Soliman, Mary R. Rooney, Lin Y. Chen

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: Excessive daytime sleepiness is a common sleep complaint among older adults. Assessment of excessive daytime sleepiness is used to screen for obstructive sleep apnea, which may be linked to atrial fibrillation (AF) and other sustained arrhythmias. Using data from the Atherosclerosis Risk in Communities (ARIC) Study cohort, we examined the association of excessive daytime sleepiness with measures of arrhythmia burden derived from a continuous ECG recording device in a community-based sample of older adults. Methods: Participating older adults (N = 2306, mean age: 78.9 ± 4.5 years, 57.8% female) wore a Zio® XT Patch for 14 days. Excessive daytime sleepiness was assessed with the Epworth Sleepiness Scale. Measures of AF and supraventricular arrhythmia burden were derived from the Zio® XT Patch. Multiple adjusted logistic, multinomial, and linear regression models were used to assess associations of excessive daytime sleepiness with AF, AF burden, and supraventricular arrhythmia burden. Results: Approximately 18% of the sample had excessive daytime sleepiness, and 8.5% had AF. After adjustment, excessive daytime sleepiness was not significantly associated with AF (odds ratio (OR), 1.20; Confidence Interval (CI), 0.81–1.75), continuous AF burden (OR, 1.36; CI, 0.85–2.16), or measures of supraventricular arrhythmia burden (SVE burden: β 0.01; 95% CI, −0.09−0.11; SVT burden: β 0.02; 95% CI, −0.04−0.08). Conclusion: In this community-based sample of older adults, excessive daytime sleepiness was not associated with measures of arrhythmia burden. Future studies with objective measures of sleep are needed to further examine the role of sleep in the development and progression of arrhythmia burden.

Original languageEnglish (US)
Pages (from-to)1223-1227
Number of pages5
JournalSleep and Breathing
Volume24
Issue number3
DOIs
StatePublished - Sep 1 2020

Bibliographical note

Funding Information:
HHSN268201700005I, HHSN268201700004I).This work was further supported by R01 HL126637 (Chen). This work was also supported by American Heart Association grant 16EIA26410001 (Alonso) and National Heart, Lung, and Blood Institute training grant T32 HL007779. Acknowledgments

Funding Information:
This study (The Atherosclerosis Risk in Communities study) was funded in whole or in part with Federal funds from the National Heart, Lung, and Blood Institute, National Institutes of Health, Department of Health and Human Services, under Contract nos. (HHSN268201700001I, HHSN268201700002I, HHSN268201700003I,

Publisher Copyright:
© 2020, Springer Nature Switzerland AG.

Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.

Keywords

  • Atrial fibrillation
  • Cardiovascular health
  • Obstructive sleep apnea
  • Sleepiness

PubMed: MeSH publication types

  • Journal Article

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