Assessment of possible thermal damage of tissue due to atherectomy by means of a mechanical debulking device

Ryan D. Lovik; John P. Abraham; Eph M. Sparrow

Assessment of possible thermal damage of tissue due to atherectomy by means of a mechanical debulking device

Ryan D. Lovik
, John P. Abraham
, Eph M. Sparrow

Mechanical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

9 Scopus citations

Abstract

In vitro and cadaver experiments, coupled with numerical simulations, were performed to assess the possibility mat orbital atherectomy might cause thermal damage of tissue. The experiments involved debulking operations on a surrogate artery and on the plaque-lined posterior tibial artery of a cadaver. Temperatures and coolant flow rates measured during these experiments enabled a numerical simulation of the debulking of a plaque-lined artery in a living human. The temperature variations from the numerical simulations were used to evaluate a thermal injury index. The resulting values of the index were found to be several orders of magnitude below the threshold value for thermal injury. It is concluded that it is extremely unlikely that the use of an orbital debulking device, the Diamondback 360°™ (Cardiovascular Systems, Inc.), can lead to thermal injury of the artery wall.

Original language	English (US)
Title of host publication	Proceedings of the ASME Summer Bioengineering Conference, SBC2008
Pages	799-800
Number of pages	2
Edition	PART B
State	Published - 2009
Event	10th ASME Summer Bioengineering Conference, SBC2008 - Marco Island, FL, United States Duration: Jun 25 2008 → Jun 29 2008

Publication series

Name	Proceedings of the ASME Summer Bioengineering Conference, SBC2008
Number	PART B

Other

Other	10th ASME Summer Bioengineering Conference, SBC2008
Country/Territory	United States
City	Marco Island, FL
Period	6/25/08 → 6/29/08

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Bioheat transfer
Debulking
Orbital atherectomy
Peripheral artery disease
Plaque-laden arteries
Thermal tissue damage

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Assessment of possible thermal damage of tissue due to atherectomy by means of a mechanical debulking device. / Lovik, Ryan D.; Abraham, John P.; Sparrow, Eph M.
Proceedings of the ASME Summer Bioengineering Conference, SBC2008. PART B. ed. 2009. p. 799-800 (Proceedings of the ASME Summer Bioengineering Conference, SBC2008; No. PART B).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Lovik, RD, Abraham, JP & Sparrow, EM 2009, Assessment of possible thermal damage of tissue due to atherectomy by means of a mechanical debulking device. in Proceedings of the ASME Summer Bioengineering Conference, SBC2008. PART B edn, Proceedings of the ASME Summer Bioengineering Conference, SBC2008, no. PART B, pp. 799-800, 10th ASME Summer Bioengineering Conference, SBC2008, Marco Island, FL, United States, 6/25/08.

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title = "Assessment of possible thermal damage of tissue due to atherectomy by means of a mechanical debulking device",

abstract = "In vitro and cadaver experiments, coupled with numerical simulations, were performed to assess the possibility mat orbital atherectomy might cause thermal damage of tissue. The experiments involved debulking operations on a surrogate artery and on the plaque-lined posterior tibial artery of a cadaver. Temperatures and coolant flow rates measured during these experiments enabled a numerical simulation of the debulking of a plaque-lined artery in a living human. The temperature variations from the numerical simulations were used to evaluate a thermal injury index. The resulting values of the index were found to be several orders of magnitude below the threshold value for thermal injury. It is concluded that it is extremely unlikely that the use of an orbital debulking device, the Diamondback 360°{\texttrademark} (Cardiovascular Systems, Inc.), can lead to thermal injury of the artery wall.",

keywords = "Bioheat transfer, Debulking, Orbital atherectomy, Peripheral artery disease, Plaque-laden arteries, Thermal tissue damage",

author = "Lovik, \{Ryan D.\} and Abraham, \{John P.\} and Sparrow, \{Eph M.\}",

year = "2009",

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pages = "799--800",

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edition = "PART B",

note = "10th ASME Summer Bioengineering Conference, SBC2008 ; Conference date: 25-06-2008 Through 29-06-2008",

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T1 - Assessment of possible thermal damage of tissue due to atherectomy by means of a mechanical debulking device

AU - Lovik, Ryan D.

AU - Abraham, John P.

AU - Sparrow, Eph M.

PY - 2009

Y1 - 2009

N2 - In vitro and cadaver experiments, coupled with numerical simulations, were performed to assess the possibility mat orbital atherectomy might cause thermal damage of tissue. The experiments involved debulking operations on a surrogate artery and on the plaque-lined posterior tibial artery of a cadaver. Temperatures and coolant flow rates measured during these experiments enabled a numerical simulation of the debulking of a plaque-lined artery in a living human. The temperature variations from the numerical simulations were used to evaluate a thermal injury index. The resulting values of the index were found to be several orders of magnitude below the threshold value for thermal injury. It is concluded that it is extremely unlikely that the use of an orbital debulking device, the Diamondback 360°™ (Cardiovascular Systems, Inc.), can lead to thermal injury of the artery wall.

AB - In vitro and cadaver experiments, coupled with numerical simulations, were performed to assess the possibility mat orbital atherectomy might cause thermal damage of tissue. The experiments involved debulking operations on a surrogate artery and on the plaque-lined posterior tibial artery of a cadaver. Temperatures and coolant flow rates measured during these experiments enabled a numerical simulation of the debulking of a plaque-lined artery in a living human. The temperature variations from the numerical simulations were used to evaluate a thermal injury index. The resulting values of the index were found to be several orders of magnitude below the threshold value for thermal injury. It is concluded that it is extremely unlikely that the use of an orbital debulking device, the Diamondback 360°™ (Cardiovascular Systems, Inc.), can lead to thermal injury of the artery wall.

KW - Bioheat transfer

KW - Debulking

KW - Orbital atherectomy

KW - Peripheral artery disease

KW - Plaque-laden arteries

KW - Thermal tissue damage

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M3 - Conference contribution

AN - SCOPUS:77952591816

SN - 9780791843215

T3 - Proceedings of the ASME Summer Bioengineering Conference, SBC2008

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BT - Proceedings of the ASME Summer Bioengineering Conference, SBC2008

T2 - 10th ASME Summer Bioengineering Conference, SBC2008

Y2 - 25 June 2008 through 29 June 2008

ER -

Assessment of possible thermal damage of tissue due to atherectomy by means of a mechanical debulking device

Abstract

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Keywords

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