Assessing bioaccessibility and bioavailability of chlorinated organophosphorus flame retardants in sediments

Huan He, Zhanqi Gao, Donglin Zhu, Jiehong Guo, Shaogui Yang, Shiyin Li, Limin Zhang, Cheng Sun

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


The distribution of chlorinated organophosphate flame retardants (OPFRs) in sediments has been well documented, but the study about their bioavailability remains lacking. This study investigated the applicability of solid phase microextraction (SPME) fiber and Tenax extraction to predict the bioavailability of two chlorinated OPFRs: tri(2-chloroisopropyl) phosphate and tri(1,3-dichloro-2-isopropyl) phosphate, in sediments. Our results showed that both SPME fiber and Tenax extracted concentrations correlated significantly with the measured concentrations in the aquatic worm (Lumbriculus variegatus). We also measured the Tenax extracted concentrations at 6 and 24 h, and a strong linear relationship between these two time durations was found. In addition, the 6-h Tenax extracted concentrations also significantly correlated with the SPME fiber extracted concentrations, and the Tenax extracted concentrations were much higher than the SPME fiber extracted concentrations. These results demonstrate the efficiency of SPME and Tenax extraction methods to predict the bioavailability of chlorinated OPFRs in sediments, and it was found that the Tenax extraction is more promising than the SPME extraction.

Original languageEnglish (US)
Pages (from-to)239-246
Number of pages8
StatePublished - 2017
Externally publishedYes

Bibliographical note

Funding Information:
The authors acknowledge the financial support from the National Natural Science Foundation of China (Nos: 41671493 , 21777067 and 21207061 ) and the Environment Monitoring Fund (No: 1303 ) of Jiangsu Province, China.

Publisher Copyright:
© 2017 Elsevier Ltd


  • Bioaccessibility
  • Bioavailability
  • Chlorinated organophosphate flame retardants
  • Sediment
  • Solid phase microextraction
  • Tenax extraction


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