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Aspirin Prevents Colorectal Cancer by Normalizing EGFR Expression
Haitao Li
, Feng Zhu
, Lisa A. Boardman
, Lei Wang
, Naomi Oi
, Kangdong Liu
, Xiang Li
, Yang Fu
, Paul J. Limburg
,
Ann M. Bode
, Zigang Dong
The Hormel Institute
Research output
:
Contribution to journal
›
Article
›
peer-review
40
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Scopus citations
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Keyphrases
Colorectal Cancer
100%
Aspirin
100%
Epidermal Growth Factor Receptor Expression
100%
Epidermal Growth Factor Receptor Inhibitors (EGFRI)
80%
Cyclooxygenase-2
60%
Immunohistochemical Staining
40%
Early Events
20%
Chemopreventive
20%
Etiology
20%
Overexpression
20%
Colorectal Tumorigenesis
20%
Gastrointestinal Tract
20%
Normal Human
20%
Preneoplastic
20%
Colorectal Cancer Risk
20%
Cancer Cases
20%
C-Jun
20%
Activator protein-1 (AP-1)
20%
Colon mucosa
20%
Egfr
20%
Frequent Use
20%
Intestinal Epithelial Cells
20%
Neoplastic Cells
20%
Cellular Accumulation
20%
Precancerous Lesions
20%
Paraffin-embedded Tissue
20%
Adenomatous Polyps
20%
ApcMin Mouse
20%
Receptor Overexpression
20%
Human Colon Epithelial Cells
20%
Mechanistic Studies
20%
Murine Fibroblasts
20%
Aspirin Intake
20%
Normal Colon
20%
Epidermal Growth Factor Receptor 2
20%
Pharmacology, Toxicology and Pharmaceutical Science
Acetylsalicylic Acid
100%
Colorectal Carcinoma
100%
Epidermal Growth Factor Receptor
100%
Cyclooxygenase 2
42%
Normal Human
14%
Precancer
14%
Transcription Factor AP 1
14%
Epidermal Growth Factor Receptor 2
14%
Adenomatous Polyp
14%
Carcinogenesis
14%
Etiology
14%