Aspirina, analgésicos y riesgo de hipertensión arterial en la Cohorte SUN

Translated title of the contribution: Aspirin, Non-Aspirin Analgesics and the Risk of Hypertension in the SUN Cohort

Juan José Beunza, Miguel Ángel Martínez-González, Maira Bes-Rastrollo, Jorge María Núñez-Córdoba, Estefanía Toledo, Álvaro Alonso

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Introduction and objectives: The use of aspirin and non-aspirin analgesics has been associated with changes in blood pressure. The aim of this study was to investigate prospectively the association between the regular use of aspirin and non-aspirin analgesics and the incidence of hypertension. Methods: The SUN project is an ongoing, continuously expanding, prospective cohort of Spanish university graduates initially free of hypertension, cardiovascular disease, diabetes and cancer; 9986 (mean age 36 years) were recruited during 1999-2005 and followed up for a mean of 51 months. Regular aspirin and non-aspirin analgesic use and the presence of other risk factors for hypertension were assessed by questionnaire at baseline, and the incidence of hypertension was assessed using biennial follow-up questionnaires. Results: In total, 543 new cases of hypertension were identified during follow-up. Regular aspirin use (i.e. 2 or more days/week) was associated with a higher risk of hypertension (hazard ratio=1.45; 95% confidence interval, 1.02-2.04) after adjustment for various confounding factors. Regular use of non-aspirin analgesic drugs was also associated with a higher risk of hypertension (hazard ratio=1.69; 95% confidence interval, 1.28-2.23). Conclusions: The regular use of aspirin and non-aspirin analgesics were both associated with an increased risk of developing hypertension, independently of other risk factors.

Translated title of the contributionAspirin, Non-Aspirin Analgesics and the Risk of Hypertension in the SUN Cohort
Original languageSpanish
Pages (from-to)286-293
Number of pages8
JournalRevista Espanola de Cardiologia
Volume63
Issue number3
DOIs
StatePublished - Mar 1 2010

Keywords

  • Analgesics
  • Aspirin
  • Cohorts
  • Hypertension
  • SUN project

Fingerprint Dive into the research topics of 'Aspirin, Non-Aspirin Analgesics and the Risk of Hypertension in the SUN Cohort'. Together they form a unique fingerprint.

  • Cite this

    Beunza, J. J., Martínez-González, M. Á., Bes-Rastrollo, M., Núñez-Córdoba, J. M., Toledo, E., & Alonso, Á. (2010). Aspirina, analgésicos y riesgo de hipertensión arterial en la Cohorte SUN. Revista Espanola de Cardiologia, 63(3), 286-293. https://doi.org/10.1016/S0300-8932(10)70087-7