Aspergillus osteomyelitis. Report of four cases and review of the literature

Kenneth J. Tack, Frank S. Rhame, Bruce Brown, Roby C. Thompson

Research output: Contribution to journalArticlepeer-review

110 Scopus citations

Abstract

Four cases of Aspergillus osteomyelitis are presented and the world literature is reviewed, for a total of 19 cases. Aspergillus osteomyelitis is largely a disease of immunosuppressed hosts, although wound and other infections in "normal" hosts are seen. In children, contiguous spread from an adjacent pulmonary infection is most common, whereas in adults hematogenous spread is the rule. The survival rate in immunocompromised patients is poor, whereas the cure rate is uniform in "normal" hosts. A combined medical-surgical therapeutic approach has been used most often and seems appropriate.

Original languageEnglish (US)
Pages (from-to)295-300
Number of pages6
JournalThe American Journal of Medicine
Volume73
Issue number2
DOIs
StatePublished - Aug 1982

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