TY - JOUR
T1 - Asparaginase II of Saccharomyces cerevisiae
T2 - Selection of four mutations that cause derepressed enzyme synthesis
AU - Kamerud, J. Q.
AU - Roon, R. J.
PY - 1986
Y1 - 1986
N2 - A positive selection method was used to isolate four Saccharomyces cerevisiae mutations that cause derepressed synthesis of asparaginase II. The four mutations (and1, and2, and3, and4) were neither closely linked to each other nor linked to previously characterized mutations (asp3, asp6) which cause the complete loss of asparaginase II activity. One of the new mutations (and4) was shown to be allelic to gdh-CR, a pleiotropic mutation which causes derepressed synthesis of a number of enzymes of nitrogen catabolism.
AB - A positive selection method was used to isolate four Saccharomyces cerevisiae mutations that cause derepressed synthesis of asparaginase II. The four mutations (and1, and2, and3, and4) were neither closely linked to each other nor linked to previously characterized mutations (asp3, asp6) which cause the complete loss of asparaginase II activity. One of the new mutations (and4) was shown to be allelic to gdh-CR, a pleiotropic mutation which causes derepressed synthesis of a number of enzymes of nitrogen catabolism.
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U2 - 10.1128/jb.165.1.293-296.1986
DO - 10.1128/jb.165.1.293-296.1986
M3 - Article
C2 - 3510190
AN - SCOPUS:0022481955
VL - 165
SP - 293
EP - 296
JO - Journal of Bacteriology
JF - Journal of Bacteriology
SN - 0021-9193
IS - 1
ER -