Artifactual FA dimers mimic FAHFA signals in untargeted metabolomics pipelines

Keyphrases

• Esters 100%
• Untargeted Metabolomics 100%
• FAHFA 100%
• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 30%
• Human Serum 20%
• Non-biological 20%
• Chemical Features 20%
• Highly Sensitive 10%
• Speciation 10%
• Glucose Homeostasis 10%
• High Resolution LC-MS 10%
• High Concentration 10%
• Insulin Sensitivity 10%
• Physiological Function 10%
• In Silico 10%
• Concentration-dependent 10%
• Lower Molar 10%
• Lipid Species 10%
• Oleic Acid 10%
• Class-based 10%
• Isomeric 10%
• Stable Isotope Labeling 10%
• Fragmentation Pattern 10%
• Misidentification 10%
• Pattern Matching 10%
• Isobaric 10%
• Authentic Standards 10%
• Endogenous Lipids 10%
• Lipid Classes 10%
• Exact Mass 10%
• Spectrum Database 10%
• Lipokines 10%
• LC-MS Untargeted Metabolomics 10%
• MS Method 10%
• Misidentified 10%

Biochemistry, Genetics and Molecular Biology

• Metabolomics 100%
• Liquid Chromatography-Mass Spectrometry 100%
• Lipid 50%
• Serum (Blood) 50%
• Tandem Mass Spectrometry 25%
• Oleic Acid 25%
• Species Differentiation 25%
• Insulin Sensitivity 25%
• Glucose Homeostasis 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Dimer 100%
• Fatty Acid 14%
• Stable Isotope 14%
• Oleic Acid 14%