Arteriographic studies of the coronary arteries in ischemic heart disease

Alan P. Thal, L. Stephen Richards, Richard Greenspan, M. John Murray

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The coronary arteries have been visualized in unanesthetized patients by injecting a radiopaque medium through a catheter into the ascending aorta. After premedication with meperidine and atropine, the catheter is introduced by way of the brachial artery and inserted until its tip lies about 2.5 cm. above the aortic valve. Special techniques have been developed in order to predetermine the phase and duration of the injection, since 40 to 55 cc. of the radiopaque medium must be injected within 0.8 to 0.6 seconds and the subsequent film exposures must be properly timed. The most convincing sign of coronary artery disease is the roentgenographic finding of occlusion of a major vessel. Of the four illustrative case histories here given, two concern patients who had been considered for cardiac surgery because of signs and symptoms of angina pectoris; the arteriographic demonstration of normal coronary systems in both cases was decisive in planning subsequent treatment. Recently injections have been made during the first half of the cardiac cycle starting at systole. This has reduced the volume of contrast material needed by half without affecting the clarity of the arteriogram. In over fifty studies there have been no complications. Copyright, 1958, By American Medical Association.

Original languageEnglish (US)
Pages (from-to)2104-2109
Number of pages6
JournalJournal of the American Medical Association
Volume168
Issue number16
DOIs
StatePublished - Dec 20 1958

Fingerprint

Contrast Media
Myocardial Ischemia
Coronary Vessels
Catheters
Meperidine
Injections
Brachial Artery
Premedication
Systole
American Medical Association
Angina Pectoris
Aortic Valve
Atropine
Thoracic Surgery
Signs and Symptoms
Aorta
Coronary Artery Disease
Therapeutics

Cite this

Arteriographic studies of the coronary arteries in ischemic heart disease. / Thal, Alan P.; Richards, L. Stephen; Greenspan, Richard; Murray, M. John.

In: Journal of the American Medical Association, Vol. 168, No. 16, 20.12.1958, p. 2104-2109.

Research output: Contribution to journalArticle

Thal, Alan P. ; Richards, L. Stephen ; Greenspan, Richard ; Murray, M. John. / Arteriographic studies of the coronary arteries in ischemic heart disease. In: Journal of the American Medical Association. 1958 ; Vol. 168, No. 16. pp. 2104-2109.
@article{d12a3a3afc024227b9e289234dde654f,
title = "Arteriographic studies of the coronary arteries in ischemic heart disease",
abstract = "The coronary arteries have been visualized in unanesthetized patients by injecting a radiopaque medium through a catheter into the ascending aorta. After premedication with meperidine and atropine, the catheter is introduced by way of the brachial artery and inserted until its tip lies about 2.5 cm. above the aortic valve. Special techniques have been developed in order to predetermine the phase and duration of the injection, since 40 to 55 cc. of the radiopaque medium must be injected within 0.8 to 0.6 seconds and the subsequent film exposures must be properly timed. The most convincing sign of coronary artery disease is the roentgenographic finding of occlusion of a major vessel. Of the four illustrative case histories here given, two concern patients who had been considered for cardiac surgery because of signs and symptoms of angina pectoris; the arteriographic demonstration of normal coronary systems in both cases was decisive in planning subsequent treatment. Recently injections have been made during the first half of the cardiac cycle starting at systole. This has reduced the volume of contrast material needed by half without affecting the clarity of the arteriogram. In over fifty studies there have been no complications. Copyright, 1958, By American Medical Association.",
author = "Thal, {Alan P.} and Richards, {L. Stephen} and Richard Greenspan and Murray, {M. John}",
year = "1958",
month = "12",
day = "20",
doi = "10.1001/jama.1958.03000160018006",
language = "English (US)",
volume = "168",
pages = "2104--2109",
journal = "JAMA - Journal of the American Medical Association",
issn = "0098-7484",
publisher = "American Medical Association",
number = "16",

}

TY - JOUR

T1 - Arteriographic studies of the coronary arteries in ischemic heart disease

AU - Thal, Alan P.

AU - Richards, L. Stephen

AU - Greenspan, Richard

AU - Murray, M. John

PY - 1958/12/20

Y1 - 1958/12/20

N2 - The coronary arteries have been visualized in unanesthetized patients by injecting a radiopaque medium through a catheter into the ascending aorta. After premedication with meperidine and atropine, the catheter is introduced by way of the brachial artery and inserted until its tip lies about 2.5 cm. above the aortic valve. Special techniques have been developed in order to predetermine the phase and duration of the injection, since 40 to 55 cc. of the radiopaque medium must be injected within 0.8 to 0.6 seconds and the subsequent film exposures must be properly timed. The most convincing sign of coronary artery disease is the roentgenographic finding of occlusion of a major vessel. Of the four illustrative case histories here given, two concern patients who had been considered for cardiac surgery because of signs and symptoms of angina pectoris; the arteriographic demonstration of normal coronary systems in both cases was decisive in planning subsequent treatment. Recently injections have been made during the first half of the cardiac cycle starting at systole. This has reduced the volume of contrast material needed by half without affecting the clarity of the arteriogram. In over fifty studies there have been no complications. Copyright, 1958, By American Medical Association.

AB - The coronary arteries have been visualized in unanesthetized patients by injecting a radiopaque medium through a catheter into the ascending aorta. After premedication with meperidine and atropine, the catheter is introduced by way of the brachial artery and inserted until its tip lies about 2.5 cm. above the aortic valve. Special techniques have been developed in order to predetermine the phase and duration of the injection, since 40 to 55 cc. of the radiopaque medium must be injected within 0.8 to 0.6 seconds and the subsequent film exposures must be properly timed. The most convincing sign of coronary artery disease is the roentgenographic finding of occlusion of a major vessel. Of the four illustrative case histories here given, two concern patients who had been considered for cardiac surgery because of signs and symptoms of angina pectoris; the arteriographic demonstration of normal coronary systems in both cases was decisive in planning subsequent treatment. Recently injections have been made during the first half of the cardiac cycle starting at systole. This has reduced the volume of contrast material needed by half without affecting the clarity of the arteriogram. In over fifty studies there have been no complications. Copyright, 1958, By American Medical Association.

UR - http://www.scopus.com/inward/record.url?scp=70349144750&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=70349144750&partnerID=8YFLogxK

U2 - 10.1001/jama.1958.03000160018006

DO - 10.1001/jama.1958.03000160018006

M3 - Article

C2 - 13598654

AN - SCOPUS:70349144750

VL - 168

SP - 2104

EP - 2109

JO - JAMA - Journal of the American Medical Association

JF - JAMA - Journal of the American Medical Association

SN - 0098-7484

IS - 16

ER -