Pulse contour analysis (PCA) was used to determine systemic arterial compliance in hypertensive subjects at basal resting conditions and during dynamic exercise on a bicycle ergometer. In 6 male patients aged 41 to 71 years (mean age 57 ± 11), large artery compliance (C1) and distal arterial compliance (C2) were assessed by analyzing the brachial artery pressure waveform and cardiac output (CO). Measurements were obtained at rest in an upright seated position on the ergometer and during exercise after a minimum of 4 minutes at 50 watts. During exercise, mean arterial pressure (MAP) increased by 19% (p < 0.001), heart rate (HR) increased by 58% (p < 0.001), and CO increased by 101% (p < 0.001). Systemic vascular resistance (SVR) fell by 53% (p < 0.01), while C1 rose by 65% (p < 0.05) and C2 rose by 265% (p < 0.05). These data indicate that the vasculature of human hypertensives retains the capacity to become more compliant with exercise.
|Original language||English (US)|
|Number of pages||5|
|Journal||Biomedical Sciences Instrumentation|
|State||Published - 1988|
|Event||Proceedings of the Twenty-Fifth Annual Rocky Mountain Bioengineering Symposium and the Twenty-Fifth International ISA Biomedical Sciences Instrumentation Symposium - Colorado Spring, CO, USA|
Duration: Apr 25 1988 → Apr 26 1988