Arterial vascular compliance in heart failure

Stanley M Finkelstein, G. E. McVeigh, D. E. Burns, P. F. Carlyle, Jay N Cohn

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations


The effects of congestive heart failure and aging on arterial vascular compliance were evaluated in 46 heart-failure patients and 48 healthy control subjects, over a 19-75-year age range. Compliance values were calculated from a modified Windkessel model of the peripheral vasculature, utilizing parameters from the pulse contour analysis of the brachial artery pressure waveform. Cardiac output was determined by thermodilution for the heart-failure patients and by dye dilution for the controls. The results show that distal vascular compliance (ml/mm Hg) is significantly lower (0.036 vs 0.0744, p < 0.001) in heart failure and systemic vacular resistance is higher (1594 vs 1381, p < 0.05), while proximal compliance is unchanged. Resistance increased and proximal and distal compliance decreased with increasing age in the controls, but only the decrease in proximal compliance is associated with increasing age in the heart-failure group.

Original languageEnglish (US)
Title of host publicationBiomedical Engineering Perspectives
Subtitle of host publicationHealth Care Technologies for the 1990's and Beyond
PublisherPubl by IEEE
Number of pages2
Editionpt 2
ISBN (Print)0879425598
StatePublished - 1990
EventProceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Philadelphia, PA, USA
Duration: Nov 1 1990Nov 4 1990

Publication series

NameProceedings of the Annual Conference on Engineering in Medicine and Biology
Numberpt 2
ISSN (Print)0589-1019


OtherProceedings of the 12th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CityPhiladelphia, PA, USA


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