Arterial elasticity as part of a comprehensive assessment of cardiovascular risk and drug treatment

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Abstract

Early cardiovascular disease can be identified in asymptomatic individuals by noninvasive evaluation of functional and structural abnormalities of the vasculature and heart. These abnomalities are usually a consequence of endothelial dysfunction. A panel of 10 tests, including small and large artery elasticity, has been used as the basis for a screening system that provides a score of 0 to 20 as a guide to the severity of disease. Using that Rasmussen score allows for stratification of patients into low, intermediate, or high risk for progression to cardiovascular morbid events. This comprehensive screening can be performed efficiently in a single room with a single technician. The sensitivity and specificity of this screening system in predicting future cardiovascular events, its superiority to traditional risk factor assessment, and its potential to track the response to therapeutic interventions must be validated in long-term follow-up studies.

Original languageEnglish (US)
Pages (from-to)217-220
Number of pages4
JournalHypertension
Volume46
Issue number1
DOIs
StatePublished - Jul 2005

Keywords

  • Arterial compliance
  • Carotid thickness
  • Exercise blood pressure
  • Microalbuminuria
  • Nitric oxide
  • Retinal vasculature

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