TY - JOUR
T1 - Aromatic hydroxylation and sulfation of 5-hydroxyflavone by Streptomyces fulvissimus
AU - Ibrahim, Abdel Rahim
AU - Abul-Hajj, Y. J.
PY - 1989/1/1
Y1 - 1989/1/1
N2 - The conversion of 5-hydroxyflavone by various microorganisms was studied. Among them, Streptomyces fulvissimus was the sole microbe which produced a new polar metabolite from 5-hydroxyflavone in addition to 5,4'-dihydroxy- and 5,3',4'-trihydroxyflavone. The structure of this polar metabolite was determined to be 5,4'-dihydroxyflavone-4'-sulfate on the basis of mass, infrared, and nuclear magnetic resonance spectroscopies. These results demonstrate that S. fulvissimus catalyzes sulfation at the 4' position of 5,4'-dihydroxyflavone.
AB - The conversion of 5-hydroxyflavone by various microorganisms was studied. Among them, Streptomyces fulvissimus was the sole microbe which produced a new polar metabolite from 5-hydroxyflavone in addition to 5,4'-dihydroxy- and 5,3',4'-trihydroxyflavone. The structure of this polar metabolite was determined to be 5,4'-dihydroxyflavone-4'-sulfate on the basis of mass, infrared, and nuclear magnetic resonance spectroscopies. These results demonstrate that S. fulvissimus catalyzes sulfation at the 4' position of 5,4'-dihydroxyflavone.
UR - https://www.scopus.com/pages/publications/0024404586
UR - https://www.scopus.com/pages/publications/0024404586#tab=citedBy
U2 - 10.1128/aem.55.12.3140-3142.1989
DO - 10.1128/aem.55.12.3140-3142.1989
M3 - Article
C2 - 2619306
AN - SCOPUS:0024404586
SN - 0099-2240
VL - 55
SP - 3140
EP - 3142
JO - Applied and environmental microbiology
JF - Applied and environmental microbiology
IS - 12
ER -