Are the insulin-like growth factors relevant to cancer?

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13 Scopus citations


Recognition of molecular pathways relevant to cancer biology have led to advances in prevention and treatment. Numerous laboratory and clinical investigations have implicated the insulin-like growth factors (IGFs) in tumourigenesis. In this review, the evidence for the involvement of IGFs in cancer is discussed. While these data are persuasive, it is clear that additional methods to regulate IGF action in cancer patients are needed to substantiate the role of this growth factor family in cancer biology.

Original languageEnglish (US)
Pages (from-to)339-345
Number of pages7
JournalGrowth Hormone and IGF Research
Issue number6
StatePublished - 2001

Bibliographical note

Copyright 2017 Elsevier B.V., All rights reserved.


  • Insulin-like growth factor receptors
  • Insulin-like growth factors
  • Neoplasms


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